Beilstein J. Org. Chem.2015,11, 328–334, doi:10.3762/bjoc.11.38
of 5.0–40 μM. The synthesized compounds do not show any antiviral activity.
Keywords: antitumor activity; click chemistry; 1,3-dipolar cycloaddition; nucleic acids; 2’-oxa-3’-aza-4’a-carbanucleosideanalogs; Introduction
Synthetic modified nucleosides are of great interest as potential new lead
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Graphical Abstract
Figure 1:
2’-Oxa-3’-aza-modified nucleosides and 2’-oxa-3’-aza-modified nucleotides.